RocE

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  • Description: amino acid permease

Gene name rocE
Synonyms
Essential no
Product amino acid permease
Function arginine, ornithine and citrulline uptake
MW, pI 51 kDa, 8.528
Gene length, protein length 1401 bp, 467 aa
Immediate neighbours rocF, rocD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RocE context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU40330

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot), membrane associated PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: induced by arginine (RocR, AhrC) PubMed, repressed by CodY PubMed
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Hahne et al. (2008) From complementarity to comprehensiveness - targeting the membrane proteome of growing Bacillus subtilis by divergent approaches. Proteomics 8: 4123-4136 PubMed
  2. Gardan R, Rapoport G, Débarbouillé M. (1995) Expression of the rocDEF operon involved in arginine catabolism in Bacillus subtilis. J Mol Biol. Jun 23;249(5): 843-56. PubMed
  3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed