sigF
168

[wiki|RNA polymerase] forespore-specific (early) [wiki|sigma factor] SigF

locus

BSU_23450

Molecular weight

29.22 kDa

5.08

Protein length

255 aaSequenceBlast

Gene length

768 bpSequenceBlast

function

transcription of [wiki|sporulation] genes (early forespore)

product

[wiki|RNA polymerase] forespore-specific (early) [wiki|sigma factor] SigF

essential

synonyms

sigF, spoIIAC

Outlinks

BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1191 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene

Coordinates

2,443,429 → 2,444,196

The protein

Protein family

[wiki|Sigma-70 factor family] (according to UniProt)

Structure

[PDB|1L0O] (complex with [protein|C8B867758330355F44C63CC284DC7AA3061FB9F1|spoIIAB], Geobacillus stearothermophilus) [pubmed|11955433]

[AF|P07860]

Paralogous protein(s)

[protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]

Expression and Regulation

Operons

genes

description

[Pubmed|22383849]

regulation

''[wiki|spoIIAA]'': expressed early during sporulation

regulatory mechanism

[protein|5A6FBAE6553343092862CB79E150F934978C32A9|sinR]: repression, in [regulon|protein:5A6FBAE6553343092862CB79E150F934978C32A9|sinR regulon]

sigma factors

[protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]: sigma factor, in [regulon|protein:CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF regulon]

[protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]: sigma factor, in [regulon|protein:5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG regulon]

[protein|DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|sigH]: sigma factor, in [regulon|protein:DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|sigH regulon]

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genes

description

[Pubmed|22383849]

regulation

''[wiki|spoIIAA]'': expressed early during sporulation

regulatory mechanism

sigma factors

[protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]: sigma factor, in [regulon|protein:5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG regulon]

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Biological materials

Mutant

BKE23450 (Δ[gene|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE23450 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CTCCACATCCATAACAAATC, downstream forward: _UP4_TAGTCTGCAGTGCAGGCTAG

BKK23450 (Δ[gene|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK23450 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CTCCACATCCATAACAAATC, downstream forward: _UP4_TAGTCTGCAGTGCAGGCTAG

labs

[wiki|Charles Moran], Emory University, NC, USA [http://www.microbiology.emory.edu/moran_c.html homepage]

References

Reviews

20833318,31350897,35638784

Original Publications

10503549,8358793,7570023,9555886,3007937,8460142,9077448,10323866,10869437,7768847,14744853,8759874,10864495,1744043,16824103,11701124,1902463,8171000,1904527,15351644,15882622,8764398,8764397,9826498,9826499,2492512,1629150,12676949,7592342,11684022,8846916,1948031,8126438,3114419,12081956,9150232,15205443,9004507,8168129,2123551,8824593,19390092,17498739,8021191,1556084,15687200,12107147,18208527,10049355,23169620,21037003,20817675,21935351,25101664,11955433,28838935,29702640,38502707

The [wiki|SigF regulon]

16497325,26506528

Page visits: 12080

Time of last update: 2024-09-30 06:05:11

Author of last update: Jstuelk

sigF 168

sigF
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