ecfA1
168
ATP-binding A1 component of [wiki|ECF transporter]s
locus
BSU_01450
Molecular weight
31.31 kDa
pI
4.77
function
uptake of micronutrients
product
[wiki|ECF transporter] (ATP-binding protein)
essential
no
ec
3.6.3.-
synonyms
ybxA, ybaD
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1122 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
150,443 → 151,288
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The protein
Protein family
[wiki|ABC transporter superfamily] (according to UniProt)
[wiki|Domains]
[wiki|ABC transporter domain] (aa 7-242) (according to UniProt)
Structure
[PDB|4HUQ] (EcfA1-EcfA2-EcfT-FolT complex of ''Lactobacillus brevis''), [Pubmed|23584589]
[AF|P40735]
Paralogous protein(s)
[protein|5ABF4F7A3D00B523F67B281241A6A8101EC60057|ecfA2]
[wiki|Localization]
membrane associated (via [protein|7DC7BD54ED425859FFD45B8B6F3522750A938835|ecfT]) [Pubmed|10092453]
Biological materials
Mutant
BKE01450 (Δ[gene|D8637043C7E2291589C966E95F94DC61B1A8AB75|ecfA1]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE01450 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGGAAAACCGGCCTCCTC, downstream forward: _UP4_AAGATGTAGAGCATCGCTAT
BKK01450 (Δ[gene|D8637043C7E2291589C966E95F94DC61B1A8AB75|ecfA1]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK01450 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGGAAAACCGGCCTCCTC, downstream forward: _UP4_AAGATGTAGAGCATCGCTAT
BP1149 ([gene|D8637043C7E2291589C966E95F94DC61B1A8AB75|ecfA1]-[gene|5ABF4F7A3D00B523F67B281241A6A8101EC60057|ecfA2]-[gene|7DC7BD54ED425859FFD45B8B6F3522750A938835|ecfT]::cat [gene|search|trp]+) available at [wiki|Jörg Stülke]'s and [wiki|Fabian Commichau]'s labs
References
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Time of last update: 2024-10-03 10:30:41
Author of last update: Jstuelk