coaE
168
dephospho-CoA kinase
locus
BSU_29060
Molecular weight
21.87 kDa
pI
4.86
function
synthesis of coenzyme A
product
dephospho-CoA kinase
essential
yes
ec
2.7.1.24
synonyms
ytaG
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0237 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,970,922 → 2,971,515
Phenotypes of a mutant
essential [Pubmed|12682299]
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The protein
Catalyzed reaction/ biological activity
3'-dephospho-CoA + ATP --> ADP + CoA + H+ (according to UniProt)
Protein family
coaE family (single member, according to UniProt)
[wiki|Domains]
DPCK domain (aa 4-197) (according to UniProt)
Structure
[PDB|1N3B] (from ''Escherichia coli'', 40% identity, 60% similarity) [Pubmed|12538896]
[AF|O34932]
Modification
phosphorylated on ser/ thr/ tyr [Pubmed|16493705]
Expression and Regulation
Operons
genes
[gene|3D6DA8B52A4CB49361E67906140696FFA1EF6099|polA]-[gene|EC96EDED2472607DFA4C5EBA054157F7832EE41C|mutM]-[gene|3BEE8E248BC583FCCB37B7A209A122DD93CD398C|ytaF]-[gene|E163A282560DB882B81E783E7E95E1960F4AE4D2|coaE]
description
[pubmed|22383849]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|23396918], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
Biological materials
Mutant
MGNA-A118 (ytaG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/118 NBRP B. subtilis, Japan]
References
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Time of last update: 2024-08-06 19:19:17
Author of last update: Jstuelk