YfkJ

• Description: general stress protein, protein tyrosine phosphatase
  
  

Gene name	yfkJ
Synonyms
Essential	no
Product	protein tyrosine phosphatase
Function	survival of ethanol stress
MW, pI	17 kDa, 4.563
Gene length, protein length	468 bp, 156 aa
Immediate neighbours	yfkK, yfkI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

protein modification, general stress proteins (controlled by SigB)

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU07880

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Protein tyrosine phosphate + H₂O = protein tyrosine + phosphate (according to Swiss-Prot)

• Protein family: low molecular weight phosphotyrosine protein phosphatase family (according to Swiss-Prot)

• Paralogous protein(s): YwlE

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O35016

• KEGG entry: [3]

• E.C. number: 3.1.3.48

Expression and regulation

• Operon: yfkJ-yfkI-yfkH (according to DBTBS)

• Sigma factor: SigA PubMed, SigB PubMed

• Regulation: induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: