YfkJ

• Description: general stress protein, protein tyrosine phosphatase, required for protection against paraquat stress
  
  

Gene name	yfkJ
Synonyms
Essential	no
Product	protein tyrosine phosphatase
Function	survival of stress conditions
Gene expression levels in SubtiExpress: yfkJ
MW, pI	17 kDa, 4.563
Gene length, protein length	468 bp, 156 aa
Immediate neighbours	yfkK, yfkI
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

protein modification, general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU07880

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Protein tyrosine phosphate + H₂O = protein tyrosine + phosphate (according to Swiss-Prot)

• Protein family: low molecular weight phosphotyrosine protein phosphatase family (according to Swiss-Prot)

• Paralogous protein(s): YwlE

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 4ETM

• UniProt: O35016

• KEGG entry: [3]

• E.C. number: 3.1.3.48

Expression and regulation

• Operon: yfkJ-yfkI-yfkH (according to DBTBS)

• Expression browser: yfkJ PubMed

• Sigma factor: SigA PubMed, SigB PubMed

• Regulation: induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: